Evolution of testing strategies for genetic toxicity
β Scribed by David Brusick
- Book ID
- 119093085
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 936 KB
- Volume
- 205
- Category
- Article
- ISSN
- 0165-1218
No coin nor oath required. For personal study only.
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## Abstract The International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) Project Committee on the Relevance and Followβup of Positive Results in In Vitro Genetic Toxicity (IVGT) Testing established an Emerging Technologies and New Strategies Workgroup to revie
By definition, short-term tests (STTs) for genetic toxicity detect genotoxic agents, not carcinogens specifically. However, there is sufficient evidence, based on mechanistic considerations alone, to say that genotoxic agents are potential carcinogens. STTs have high statistical power, are almost al