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Evolution of pathogenicity and sexual reproduction in eight Candida genomes

✍ Scribed by Reedy, Jennifer L.; Butler, Geraldine; Rasmussen, Matthew D.; Lin, Michael F.; Santos, Manuel A. S.; Sakthikumar, Sharadha; Munro, Carol A.; Rheinbay, Esther; Grabherr, Manfred; Forche, Anja

Book ID
109898216
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
466 KB
Volume
459
Category
Article
ISSN
0028-0836

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We present a model which describes mutation, selection and sexual reproduction in an infinite haploid population with a finite genome. Each generation is described using an approximation which assures a certain persistent form of the distribution of the number of deleterious elements. The steady sta