Evolution of parallel β/α-barrel enzyme family lightened by structural data on starch-processing enzymes

High resolution structure and sequence o

High resolution structure and sequence of T. aurantiacus Xylanase I: Implications for the evolution of thermostability in family 10 xylanases and enzymes with βα-barrel architecture

✍ L. Lo Leggio; S. Kalogiannis; M.K. Bhat; R.W. Pickersgill 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 469 KB 👁 1 views

Xylanase I is a thermostable xylanase from the fungus Thermoascus aurantiacus, which belongs to family 10 in the current classification of glycosyl hydrolases. We have determined the three-dimensional X-ray structure of this enzyme to near atomic resolution (1.14 A ˚) by molecular replacement, and t