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Evolution of nucleotide-binding proteins

✍ Scribed by BLAKE, C. C. F.


Book ID
109692132
Publisher
Nature Publishing Group
Year
1974
Tongue
English
Weight
273 KB
Volume
250
Category
Article
ISSN
0028-0836

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Histidine triad (HIT) proteins were until recently a superfamily of proteins that shared only sequence motifs. Crystal structures of nucleotide-bound forms of histidine triad nucleotide-binding protein (Hint) demonstrated that the conserved residues in HIT proteins are responsible for their distinct