To clarify the virological differences in patients with chronic hepatitis C virus (HCV) infection with and without liver damage, we assessed HCV markers in 306 patients from a rural area of Japan. Genotypes of HCV RNA were determined by polymerase chain reaction, and levels of RNA were determined by
Evolution of Hepatitis C Virus Quasispecies in Children with Chronic Hepatitis C
β Scribed by M. Gerotto; M. Resti; F. Dal Pero; I. Migliorato; A. Alberti; F. Bortolotti
- Book ID
- 107705428
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 113 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0300-8126
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The quasispecies nature of hepatitis C virus (HCV) in patients with mixed HCV subtype infection was compared with that in patients with single HCV subtype infection. The number of HCV quasispecies was compared between 35 patients with mixed HCV subtype infection and 83 patients with single subtype i
Evolution of hepatitis C quasispecies may be one mechanism by which fibrosing cholestatic hepatitis develops after liver transplantation. In this study, we compared changes in quasispecies complexity and/or divergence in (1) hepatitis C-infected immunosuppressed transplant recipients and in immunoco