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Evolution of functionality in lattice proteins

โœ Scribed by Paul D Williams; David D Pollock; Richard A Goldstein

Book ID
108488161
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
296 KB
Volume
19
Category
Article
ISSN
1093-3263

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## Abstract Directed evolution has been successfully used to engineer proteins for basic and applied biological research. However, engineering of novel protein functions by directed evolution remains an overwhelming challenge. This challenge may come from the fact that multiple simultaneously or sy