Evolution of dose and response to botulinum toxin A in cervical dystonia: a multicenter study
✍ Scribed by Pedro J. Garcia Ruiz; Juan Carlos Martínez Castrillo; Juan A. Burguera; Victor Campos; Alfonso Castro; Esther Cancho; Jose Chacón; Jaime Hernández Vara; Javier Lopez del Val; Elena Lopez Garcia; Francesc Miquel; Pilar Sanz; Lydia Vela
- Book ID
- 106095182
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 135 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0340-5354
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## Abstract Efficacy of botulinum toxin type B (BoNT B) for the treatment of type A‐resistant (AR) and non‐A‐resistant (NAR) cervical dystonia (CD) has been demonstrated in several single injection studies. There is little data available on long‐term therapy with repeated injection sessions and it
## Abstract Botulinum toxin (BTX) injection is considered the treatment of choice for patients with cervical dystonia (torticollis). We conducted a pilot, open‐label, dose‐escalation study with BTX type B in 12 patients who no longer responded clinically to injections with BTX type A. At the doses
## Abstract We studied 20 patients with cervical dystonia who had started to respond poorly to botulinum toxin A (BTXA) injections after an initial good response. All patients had extensor digitorum brevis (EDB) tests performed in addition to BTXA immunoprecipition assay (IPA) and mouse bioassay (M