𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Evolution of Crimean-Congo Hemorrhagic Fever virus

✍ Scribed by Vassiliki Anagnostou; Anna Papa

Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
355 KB
Volume
9
Category
Article
ISSN
1567-1348

No coin nor oath required. For personal study only.

✦ Synopsis

The evolutionary patterns of each genome RNA segment of Crimean-Congo Hemorrhagic Fever virus (CCHFV) were investigated. Nucleotide sequences from 40 CCHFV strains isolated during time period spanning from 1956 to 2003 were tested. It was found that there is not any global molecular clock ticking at the same rate for CCHFV strains; however a local clock is applicable in S RNA segment among strains in the individual clades. African strains seem to evolve faster than strains from other geographic regions. In the comparative study of 18 strains it was found that the evolution rates of S, M and L segments are 0.34 x 10(-4), 1.22 x 10(-4), and 1.01 x 10(-4), respectively. Many discrepancies in clustering were seen, most probably caused by reassortment events, leading in complex patterns of evolution.

📜 SIMILAR VOLUMES

Crimean-Congo hemorrhagic fever in Pakis
Crimean-Congo hemorrhagic fever in Pakistan
✍ Mohammad A. Rai; Mohammad R. Khanani; Haider J. Warraich; Abbas Hayat; Syed H. A 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB

## Abstract Crimean‐Congo virus, the causative agent of Crimean‐Congo Virus Fever (CCVF) is endemic in Pakistan. Cases are documented sporadically ever year, mostly at and around the time of Eid‐ul‐Adha, an Islamic festival, celebrated on day 10 through 13 of the 12th month of each lunar calendar y

Genetic analysis of crimean-congo hemorr
Genetic analysis of crimean-congo hemorrhagic fever virus in Iran
✍ Sadegh Chinikar; Stine-Mari Persson; Marie Johansson; Linda Bladh; Mehdi Goya; B 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB

## Abstract Crimean‐Congo hemorrhagic fever (CCHF) is a potentially fatal disease caused by a tick‐borne virus in the family __Bunyavridae__. The disease occurs in parts of Africa, Asia, Middle East, and Eastern Europe. During recent years, an increasing number of human CCHF cases have been diagnos

Recombinant nucleoprotein-based serologi
Recombinant nucleoprotein-based serological diagnosis of Crimean–Congo hemorrhagic fever virus infections
✍ Masayuki Saijo; Qing Tang; Bawudong Shimayi; Lei Han; Yuzhen Zhang; Muer Asiguma 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB

## Abstract An enzyme‐linked immunosorbent assay (ELISA) using recombinant nucleoprotein (rNP) was reported for the detection of immunoglobulin G (IgG) antibodies to Crimean–Congo hemorrhagic fever (CCHF) virus (CCHFV). The immunoglobulin M (IgM)‐capture ELISA was developed for the diagnosis of CCH

Crimean-Congo hemorrhagic fever virus de
Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response
✍ Ida Andersson; Helen Karlberg; Mehrdad Mousavi-Jazi; Luis Martínez-Sobrido; Frie 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB

## Abstract As a first line of defence against virus infection, mammalian cells elicit an innate immune response, characterized by secretion of type I interferons and the up‐regulation of interferon stimulated genes. Many viruses down‐regulate the innate immune responses in order to enhance their v

Crimean-congo hemorrhagic fever virus–ti
Crimean-congo hemorrhagic fever virus–tick survey in endemic areas in Bulgaria
✍ Ivanka Gergova; Metodi Kunchev; Bozhin Kamarinchev 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB

## Abstract The Balkan Peninsula and Bulgaria in particular, is a well‐known endemic region for Crimean‐Congo hemorrhagic fever (CCHF). This study describes the prevalence of Crimean‐Congo hemorrhagic fever virus (CCHFV) among tick populations from areas, previously recognized with emerging cases o