✦ LIBER ✦

Evolution of biomolecular networks — lessons from metabolic and protein interactions

✍ Scribed by Yamada, Takuji; Bork, Peer

Book ID: 109959262
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 764 KB
Volume: 10
Category: Article
ISSN: 1471-0072
DOI: 10.1038/nrm2787

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The evolution of domain arrangements in

The evolution of domain arrangements in proteins and interaction networks

✍ E. Bornberg-Bauer; F. Beaussart; S. K. Kummerfeld; S. A. Teichmann; J. Weiner 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 404 KB

Dissecting the roles of individual inter

Dissecting the roles of individual interactions in protein stability: Lessons from a circularized protein

✍ David P. Goldenberg 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 860 KB

Evolutionary Genomics and Systems Biolog

Evolutionary Genomics and Systems Biology (Caetano-Anolles/Evolutionary Genomics) || Single-Gene and Whole-Genome Duplications and the Evolution of Protein-Protein Interaction Networks

✍ Caetano-AnollÃ©s, Gustavo 📂 Article 📅 2010 🏛 John Wiley & Sons, Inc. 🌐 English ⚖ 187 KB 👁 1 views

A comprehensive, authoritative look at an emergent area in post-genomic science Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. *Evolutionary Genomics and Systems Biology* is the first full-length book to blend established and

Metabolic engineering and protein direct

Metabolic engineering and protein directed evolution increase the yield of L-phenylalanine synthesized from glucose in Escherichia coli

✍ José Luis Báez-Viveros; Joel Osuna; Georgina Hernández-Chávez; Xavier Soberón; F 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 575 KB

## Abstract L‐phenylalanine (L‐Phe) is an aromatic amino acid with diverse commercial applications. Technologies for industrial microbial synthesis of L‐Phe using glucose as a starting raw material currently achieve a relatively low conversion yield (__Y~Phe/Glc~__). The purpose of this work was to

Prediction of plasma protein binding dis

Prediction of plasma protein binding displacement and its implications for quantitative assessment of metabolic drug–drug interactions from in vitro data

✍ Hege Christensen; Mark Baker; Geoffrey T. Tucker; Amin Rostami-Hodjegan 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB 👁 1 views

Although displacement from plasma protein binding (dPB) is usually of little clinical significance, it should be taken into account when interpreting changes in total plasma concentrations of drugs subject to metabolically based drug-drug interactions (mDDI). The aim of this study was to develop an