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Evolution of 11β-hydroxysteroid dehydrogenase-type 1 and 11β-hydroxysteroid dehydrogenase-type 3

✍ Scribed by Michael E. Baker

Book ID
113621951
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
816 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract Glucocorticoids are potent regulators of inflammation exerting permissive, stimulatory, and suppressive effects. Glucocorticoid access to intracellular receptors is regulated by the activity of two distinct enzymes known as 11β‐hydroxysteroid dehydrogenase (11βHSD) Type 1 and Type 2, wh