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Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the α2-macroglobulin receptor

✍ Scribed by Torsten Kristensen; Søren K. Moestrup; Jørgen Gliemann; Lone Bendtsen; Ole Sand; Lars Sottrup-Jensen


Book ID
115923348
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
659 KB
Volume
276
Category
Article
ISSN
0014-5793

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Low density lipoprotein receptor-related protein (LRP) participates in the uptake and degradation of several ligands implicated in neuronal pathophysiology including apolipoprotein E (apoE), activated ␣ 2 -macroglobulin (␣ 2 M\*) and ␤-amyloid precursor protein (APP). The receptor is expressed in a