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Evidence that lipid peroxidation products bind to DNA in liver cells

✍ Scribed by En-Hua Cao; Xi-Qi Liu; Long-Gui Wang; Ju-Jun Wang; Na-Fei Xu

Book ID
115741600
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
562 KB
Volume
1259
Category
Article
ISSN
0005-2760

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## Abstract ## Objective The lipid peroxidation product 4‐hydroxynonenal (HNE) is prominently produced in osteoarthritic (OA) synovial cells, but its specific contribution to cartilage destruction is not understood. This study was designed to test whether HNE signaling and binding are involved in