## Abstract In this article we show that 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~) stimulates the activity of the class IA phosphatidylinositol 3‐kinase PI3Kα and its downstream target Akt in HL60, U937 and THP‐1 myeloid leukaemic cell lines. Furthermore, we show that the classical nuclear vit
✦ LIBER ✦
Evidence that calcitonin plays a role in the postnatal increase of serum 1α, 25-dihydroxyvitamin D
✍ Scribed by T. Nishioka; T. Yasuda; H. Niimi; H. Nakajima
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 585 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0340-6997
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## Abstract 9__‐cis__‐Retinoic acid (9cRA) and 1α,25‐dihydroxyvitamin D~3~ (1,25D) show promise as potential chemopreventive agents. We examined 9cRA and 1,25D, alone and in combination, for their potential to inhibit carcinogen (NNK)‐induced lung carcinogenesis in A/J mice. A/J mice (__n__ = 14/gr