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Evidence of Zinc Protection against 2,5-Hexanedione Neurotoxicity: Correlation of Neurobehavioral Testing with Biomarkers of Excretion

✍ Scribed by M.Luisa Mateus; Ana P.M.dos Santos; M.Camila C Batoréu


Book ID
117329985
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
171 KB
Volume
23
Category
Article
ISSN
0161-813X

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Evidence for zinc protection against 2,5
✍ M. L. Mateus; A. P. M. Dos Santos; M. C. Batoreu 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 59 KB 👁 1 views

The protective role of zinc against the toxic effects of 2, 5-hexanedione (2,5-HD), the main neurotoxic metabolite of n-hexane, was investigated by studying the interference of zinc on the toxicokinetics of 2,5-HD. Six groups of Wistar rats were exposed for 3 days to diets containing 2,5-HD, zinc ch