Evidence of tumor heterogeneity in cervical cancers and lymph node metastases as determined by flow cytometry
β Scribed by Hoa N. Nguyen; Bernd-Uwe Sevin; Hervy E. Averette; Reinaldo Ramos; Parvin Ganjei; James Perras
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 731 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract With the aim of distinguishing neoplastic cell subβpopulations of different prognostic and diagnostic significance, dualβparameter measurements (DNA/protein) have been simultaneously determined in a (256, 256) channel matrix in lung samples derived from 110 patients affected by neoplast
Expression of epidermal growth factor receptor (EGFR) was quantified by 2-color flow cytometry in cervical cancer (n = 73) and normal cervical epithelium (n = 11). EGFR was determined using a murine monoclonal EGFR antibody, and number of bound antibodies was quantified adding calibration beads with
Flow cytometric DNA content measurements have demonstrated extensive DNA ploidy heterogeneity in primary breast carcinomas. However, little is known at the molecular level about the clonal relationship between these tumor cell subpopulations, or about the molecular genetic changes associated with an