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Evidence of the involvement of the DHFR gene in nonsyndromic cleft lip with or without cleft palate

✍ Scribed by Martinelli, Marcella; Girardi, Ambra; Cura, Francesca; Carinci, Francesco; Morselli, Paolo Giovanni; Scapoli, Luca

Book ID: 121826929
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 191 KB
Volume: 57
Category: Article
ISSN: 1769-7212
DOI: 10.1016/j.ejmg.2013.12.002

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## Abstract **BACKGROUND:** Nonsyndromic cleft lip with or without cleft palate (NCL/P) is a common structural malformation with a complex and multifactorial etiology. It has been shown that maternal psychological stress in the periconceptional period can contribute to an increase in the risk of NC