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Evidence of Peripheral Blood-Derived, Plastic-Adherent CD34−/low Hematopoietic Stem Cell Clones with Mesenchymal Stem Cell Characteristics

✍ Scribed by Ralf Huss; Claudia Lange; Eva M. Weissinger; Hans-Jochem Kolb; Karin Thalmeier


Book ID
111843246
Publisher
AlphaMed Press
Year
2000
Tongue
English
Weight
330 KB
Volume
18
Category
Article
ISSN
1066-5099

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The physiological approach suggests that an environment associating the mesenchymal stromal cells (MSC) and low O 2 concentration would be most favorable for the maintenance of hematopoietic stem cells (HSCs) in course of ex vivo expansion of hematopoietic grafts. To test this hypothesis, we perform