Evidence of Local Eosinophil Activation and Altered Mucosal Permeability in Collagenous Colitis
β Scribed by Yesuf Taha; Marie Carlson; Magnus Thorn; Lars Loof; Yngve Raab
- Book ID
- 110295041
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 874 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0163-2116
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## Background: Cathepsin g (cat-g) is a neutrophil serine-protease found in the colonic lumen of ulcerative colitis (uc) patients. cat-g is able to activate protease-activated receptor-4 (par(4) ) located at the apical side of enterocytes, leading to epithelial barrier disruption. however, the mech