✦ LIBER ✦

Evidence of intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells

✍ Scribed by Mourant, Judith R. ;Hielscher, Andreas H. ;Eick, Angelia A. ;Johnson, Tamara M. ;Freyer, James P.

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 192 KB
Volume: 84
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19981225)84:6<366::aid-cncr9>3.0.co;2-7

No coin nor oath required. For personal study only.

✦ Synopsis

Background:

The objective of this study was to determine whether there are intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells from a multistep carcinogenesis model.

Methods:

Wavelength-dependent and polarization-dependent light scattering properties of cell suspensions were measured.

Results:

Statistically significant differences were found between the tumorigenic and nontumorigenic cells. conclusions. differences in the light scattering properties of tumorigenic and nontumorigenic cells are attributed to a change in the average size of the scattering centers on the order of a few ten of nanometers. this work is relevant to the development of noninvasive optical methods for cancer diagnosis.

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