Evidence of Early Ovarian Aging in Fragile X Premutation Carriers
โ Scribed by Welt, C. K.; Smith, P. C.; Taylor, A. E.
- Book ID
- 120277521
- Publisher
- Endocrine Society
- Year
- 2004
- Tongue
- English
- Weight
- 143 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0021-972X
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There have been contradictory ยฎndings in the fragile X (fraX) literature about possible neurocognitive and psychological symptoms due to the fraX premutation (pM). The purpose of the present study was to investigate the relationship between CGG repeat length and neurobehavioral functioning in carrie
## Abstract Since only 20% of female fragile X premutation carriers develop premature ovarian failure (POF, i.e., amenorrhea before age of 40 years), and since X chromosome inactivation (XCI) determines the phenotypic severity of full mutation women, we reasoned that the development of POF in fragi