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Evidence of a correlation between mannose binding lectin and celiac disease: a model for other autoimmune diseases

✍ Scribed by Michele Boniotto; Laura Braida; Valentina Baldas; Tarcisio Not; Alessandro Ventura; Serena Vatta; Oriano Radillo; Francesco Tedesco; Selvaggia Percopo; Marcella Montico; Antonio Amoroso; Sergio Crovella


Book ID
105796266
Publisher
Springer
Year
2005
Tongue
English
Weight
291 KB
Volume
83
Category
Article
ISSN
0946-2716

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✍ Julie A. Trulson; Glenn L. Millhauser πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 162 KB πŸ‘ 3 views

The tumor suppresser protein p53 has been called the "guardian of the genome." DNA damage induces p53 to either halt the cell cycle, allowing for repair, or initiate apoptosis. P53 is mutated in over 50% of human tumors and it has been proposed that many tumorigenic mutations are deleterious to p53