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Evidence of 1,25-dihydroxyvitamin D synthesis by the rat Walker carcinosarcoma 256

✍ Scribed by M.L. Traba; F. Risco; J. Hurtado; F. de Miguel; P. Esbrit; A. Rapado


Book ID
118022812
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
389 KB
Volume
53
Category
Article
ISSN
0304-3835

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Cultured microglial cells were examined for their ability to metabolize 25-hydroxyvitamin D, (25-(OH) D,). Upon exposure to lipopolysaccharide, microglial cells produced a vitamin D metabolite which comigrated with synthetic 1,25-dihydroxyvitamin D, (1,25-(OH),D,) in two different systems of high pe