The role of the idiotypic network in the
β
Edna Mozes; Stefan Brocke; Yehuda Shoenfeld; Shlomo Mendlovic
π
Article
π
1989
π
John Wiley and Sons
π
English
β 563 KB
Systemic lupus erythematosus (SLE) has been induced in C3H.SW mice by their immunization with a human monoclonal anti-DNA antibody that bears a common idiotype-16/6 Id. Following immunization, high levels of murine anti-l6/6 and anti-anti-l6/6 antibodies were detected in the sera of the immunized mi