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Evidence from Solid-State NMR for Nonhelical Conformations in the Transmembrane Domain of the Amyloid Precursor Protein

✍ Scribed by Lu, Jun-Xia; Yau, Wai-Ming; Tycko, Robert


Book ID
119208087
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
359 KB
Volume
100
Category
Article
ISSN
0006-3495

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There is currently a great deal of interest in the early events in protein folding. Two issues that have generated particular interest are the nature of the unfolded state under native conditions and the role of local interactions in folding. Here, we report the results of a study of a set of peptid