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Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes

✍ Scribed by Max T. Baker; Maria T. Vasquez; Chiang Chao-Kuo

Book ID
115782089
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
913 KB
Volume
41
Category
Article
ISSN
0006-2952

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The localization of the form of cytochrome P-450 that is induced by phenobarbital was studied by direct immunofluorescence in the hepatocytes of rats pretreated with phenobarbital in comparison with saline-treated rats. Specific fluorescence was seen in the hepatocyte cytoplasm in saline-and phenoba