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Evidence for the role of cell stiffness in modulation of volume-regulated anion channels

โœ Scribed by F. J. Byfield; B. D. Hoffman; V. G. Romanenko; Y. Fang; J. C. Crocker; I. Levitan


Book ID
111383477
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
266 KB
Volume
187
Category
Article
ISSN
1748-1708

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The role of matrix stiffness in regulati
โœ Rebecca G. Wells ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 625 KB

Matrix stiffness (resistance to deformation), one of the many mechanical forces acting on cells, is increasingly appreciated as an important mediator of cell behavior. It regulates cell signaling broadly, with effects on growth, survival, and motility. Although the stiffness optima for different kin