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Evidence for the regulation of the activity of protein kinase C through changes in membrane properties

✍ Scribed by Richard M. Epand; Raquel F. Epand; Bryan T. -C. Leon; Fredric M. Menger; J. F. Kuo


Book ID
112483915
Publisher
Springer
Year
1991
Tongue
English
Weight
314 KB
Volume
11
Category
Article
ISSN
0144-8463

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## Abstract Recently, we succeeded in establishing a transgenic mouse line which expressed high levels of protein kinase C (PKC)–alpha in thymocytes at the mRNA level with disproportionately small increases at the protein level. The transgenic PKC‐alpha was nevertheless functionally active for indu