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Evidence for the importance of a positive charge and an α-helical structure of the C-terminus for biological activity of human IL-6

✍ Scribed by Claudia Lütticken; Alex Krüttgen; Carsten Möller; Peter C. Heinrich; Stefan Rose-John


Book ID
115924806
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
315 KB
Volume
282
Category
Article
ISSN
0014-5793

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Liposomes consisting of egg yolk phosphatidylcholine and hydrophobic peptides Nps-and C1--+H,-(Met-Met-Leu),-OEt ( n = 6-10) with various polypeptide chain lengths were prepared by the sonication method. The conformation of the peptides incorporated into the liposomes was examined by CD spectroscopy