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Evidence for the direct role of acetylcholinesterase in neurite outgrowth in primary dorsal root ganglion neurons

✍ Scribed by John W. Bigbee; Karun V. Sharma; Ellen L.-P. Chan; Oliver Bögler

Book ID
113994833
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
815 KB
Volume
861
Category
Article
ISSN
0006-8993

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Acetylcholinesterase (AChE) can promote neurite outgrowth through a mechanism that is independent of its role in hydrolyzing the neurotransmitter acetylcholine. It has been proposed that this neuritogenic capacity of AChE may result from its intrinsic capacity to function in adhesion. In this study