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Evidence for the Activation of Vitamin D Compounds in the Skin by Side-Chain Hydroxylation

✍ Scribed by Gniadecki, Robert ;Calverley, Martin J.


Book ID
111262503
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
367 KB
Volume
82
Category
Article
ISSN
0901-9928

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## Abstract Our recent studies have shown that the vitamin D analog Ro‐26‐9228 restores bone mineral density without inducing hypercalcemia in osteopenic rats. Our ex vivo experiments demonstrated that the analog upregulated gene expression in trabecular bone but not in the duodenum of female rats.