Evidence for specific, simple numeric abnormalities as primary karyotypic changes in ovarian carcinoma

Simple numeric abnormalities as primary

Simple numeric abnormalities as primary karyotype changes in ovarian carcinoma

✍ Floyd H. Thompson; Yun Liu; Julia Emerson; Ronald Weinstein; Rosemary Makar; Jef 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

## Abstract Simple near‐diploid karyotypes in ovarian cancer may indicate either primary alterations related to tumor pathogenesis or abnormalities associated with early tumor progression. We have identified a series of 13 epithelial ovarian tumors with very simple karyotypes. Specifically, these k