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Evidence for radiosensitizing by gliotoxin in HL-60 cells: implications for a role of NF-κB independent mechanisms

✍ Scribed by Baust, H; Schoke, A; Brey, A; Gern, U; Los, M; Schmid, R M; Röttinger, E M; Seufferlein, T


Book ID
110068055
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
492 KB
Volume
22
Category
Article
ISSN
0950-9232

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The transcriptional regulation of the fibronectin (FN) gene in hepatoma cells by phorbol myristate acetate (PMA) was investigated. PMA increased the synthesis and mRNA levels of FN and its promoter activity in Hep3B hepatoma cells. The PMA-induced activation of FN expression was blocked by a protein