Nonsyndromic cleft palate (CP) is a common birth defect with a complex and heterogeneous etiology involving both genetic and environmental risk factors. We conducted a genome-wide association study (GWAS) using 550 case-parent trios, ascertained through a CP case collected in an international consor
✦ LIBER ✦
Evidence for plasticity genotypes in a gene–gene–environment interaction: the TRAILS study
✍ Scribed by E. Nederhof; E. M. C. Bouma; H. Riese; O. M. Laceulle; J. Ormel; A. J. Oldehinkel
- Book ID
- 111273396
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 547 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1601-1848
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## Abstract Genetic association studies achieve an unprecedented level of resolution in mapping disease genes by genotyping dense single nucleotype polymorphisms (SNPs) in a gene region. Meanwhile, these studies require new powerful statistical tools that can optimally handle a large amount of info