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Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity

✍ Scribed by Caixas, Umbelina; Antunes, Alexandra M.M.; Marinho, Aline T.; Godinho, Ana L.A.; Grilo, Nádia M.; Marques, M. Matilde; Oliveira, M. Conceição; Branco, Teresa; Monteiro, Emília C.; Pereira, Sofia A.

Book ID
120082151
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
761 KB
Volume
301
Category
Article
ISSN
0300-483X

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## Abstract High hyperdiploidy (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) is characterized by nonrandom multiple trisomies and tetrasomies involving in particular chromosomes X, 4, 6, 8, 10, 14, 17, 18, and 21. This characteristic karyotypic pattern, the most common in pediat