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Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)

✍ Scribed by McCracken, J T; Smalley, S L; McGough, J J; Crawford, L; Del’Homme, M; Cantor, R M; Liu, A; Nelson, S F


Book ID
110059230
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
126 KB
Volume
5
Category
Article
ISSN
1359-4184

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Tandem duplication polymorphism upstream
✍ Seaman, M.I.; Fisher, J.B.; Chang, F.-M.; Kidd, K.K. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 20 KB 👁 2 views

The dopamine D4 receptor (DRD4) is a member of the D2-like dopamine receptor family. Polymorphisms at the DRD4 gene have been examined for association with a wide range of neuropsychiatric disorders and normal behavioral variation. The DRD4 gene is unusual in its high amount of expressed polymorphis