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Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration

โœ Scribed by D.R. Britton; P. Curzon; R.G. Mackenzie; J.W. Kebabian; J.E.G. Williams; D. Kerkman

Book ID
113224223
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
520 KB
Volume
39
Category
Article
ISSN
0091-3057

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Effect of cocaine self-administration on dopamine D2 receptors in rhesus monkeys
โœ Rodney J. Moore; Sharon L. Vinsant; Michael A. Nader; Linda J. Porrino; David P. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 279 KB ๐Ÿ‘ 2 views

The present study used autoradiography to examine the effects of chronic self-administration of cocaine on the density of dopamine D 2 receptors in nonhuman primates. Three rhesus monkeys intravenously self-administered an average of 1.35 mg/kg cocaine per day for 18-22 months until they were euthan