## Abstract ## Objective Arthritis is a common manifestation in systemic lupus erythematosus (SLE), appearing in ∼85% of patients. Often, the polyarthritis at presentation of SLE cannot be distinguished from rheumatoid arthritis (RA) by physical examination or history. Indeed, physicians initially
Evidence for gene–gene epistatic interactions among susceptibility loci for systemic lupus erythematosus
✍ Scribed by Travis Hughes; Adam Adler; Jennifer A. Kelly; Kenneth M. Kaufman; Adrienne H. Williams; Carl D. Langefeld; Elizabeth E. Brown; Graciela S. Alarcón; Robert P. Kimberly; Jeffrey C. Edberg; Rosalind Ramsey-Goldman; Michelle Petri; Susan A. Boackle; Anne M. Stevens; John D. Reveille; Elena Sanchez; Javier Martín; Timothy B. Niewold; Luis M. Vilá; R. Hal Scofield; Gary S. Gilkeson; Patrick M. Gaffney; Lindsey A. Criswell; Kathy L. Moser; Joan T. Merrill; Chaim O. Jacob; Betty P. Tsao; Judith A. James; Timothy J. Vyse; Marta E. Alarcón-Riquelme; BIOLUPUS Network; John B. Harley; Bruce C. Richardson; Amr H. Sawalha
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 186 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that predominantly affects women. Despite isolated reports of patients with coexisting Klinefelter's syndrome (47,XXY) and SLE, no association of Klinefelter's syndrome with SLE or any other autoimmune dis