Evidence for elevated telomerase activity in small cell carcinoma of the bladder
β Scribed by C Selli; S Gelmini; C.A Scott; A Crisci; G Giannarini; C Orlando
- Book ID
- 117263062
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 165 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0090-4295
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## METHODS. The authors used a polymerase chain reaction (PCR)-based telomeric repeat amplification protocol (TRAP) assay to determine the presence of te-Department of Urology, Mount Sinai School of lomerase activity in voided urine samples from patients with known but yet un-Medicine, New York, N
Precise diagnosis of well-differentiated hepatocellular carcinoma (HCC) is sometimes difficult to establish. Telomerase activity was examined by telomeric-repeat-amplification protocol (TRAP) in 37 HCC nodules smaller than 3 cm in diameter, including 24 fine-needle-aspiration biopsy specimens, 22 no
## Background: Telomerase is an enzyme that can reconstitute the ends (telomeres) of chromosomes after cell division and thus circumvent the cumulative damage that occurs in normal adult somatic cells during successive mitotic cycles. recently, it has been proposed that this enzyme should, therefor