𝔖 Bobbio Scriptorium
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Evidence for dual physiological forms of ergosterol in Saccharomyces cerevisiae

✍ Scribed by B. G. Adams; L. W. Parks

Book ID
102878783
Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
594 KB
Volume
70
Category
Article
ISSN
0021-9541

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✦ Synopsis

Data obtained from acid hydrolysis and extraction of yeast have demonstrated that routine saponification does not recover total sterol from the cells. This suggests the existence of a form of ergosterol resistant to saponification. Time course analyses of sterol synthesis by resting cell suspensions reveal an inverse relationship between the amounts of base labile and acid labile forms of sterol. These data give strong presumptive evidence for dual forms of ergosterol which are interconvertible according to the respiratory state of the cell.

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Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium
✍ Andreasen, A. A. ;Stier, T. J. B. πŸ“‚ Article πŸ“… 1953 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 726 KB

Past work in this laboratory has shown that the stationary populations of 8. cerevisiae produced in a yeast extract medium during serial transfer under continuous anaerobic conditions mere quite small, while excellent growth occurred in the presence of oxygen (Brockmann and Stier, '47). It was also