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Evidence for distinct regulation processes in the aclacinomycin- and doxorubicin-mediated differentiation of human erythroleukemic cells

โœ Scribed by Franck Morceau; Anne Aries; Rachid Lahlil; Laetitia Devy; Jean-Claude Jardillier; Pierre Jeannesson; Chantal Trentesaux


Book ID
115784508
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
896 KB
Volume
51
Category
Article
ISSN
0006-2952

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## Abstract In the present study, we have sought to determine whether a given signal transduction pathway can have diverse effects on subpopulations of cells of a lineage depending upon the stage of differentiation. To test this hypothesis, we selected the cyclic adenosine monophosphate (cAMP) sign