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Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice

✍ Scribed by Okamoto, Ikuhiro; Arnaud, Danielle; Le Baccon, Patricia; Otte, Arie P.; Disteche, Christine M.; Avner, Philip; Heard, Edith

Book ID
109894938
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
449 KB
Volume
438
Category
Article
ISSN
0028-0836

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De novo DNA methylation independent esta
De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes
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## Abstract In female mouse embryos, the paternal X chromosome (Xp) is preferentially inactivated during preimplantation development and trophoblast differentiation. This imprinted X‐chromosome inactivation (XCI) is partly due to an activating imprint on the maternal X chromosome (Xm), which is set