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Evidence for Cadmium Uptake through Nramp2: Metal Speciation Studies with Caco-2 Cells

โœ Scribed by Fred Elisma; Catherine Jumarie


Book ID
115588306
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
105 KB
Volume
285
Category
Article
ISSN
0006-291X

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109Cd transport was studied in the highly differentiated TC7 clone of the enterocytic-like Caco-2 cells grown on filters. Accumulation curves for 0.3 microM 109Cd over 12 h from the apical (AP) or the basal (BL) sides revealed a three-step mechanism involving: 1) a zero-time accumulation Ao; 2) a fa