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Evidence for base excision repair processing of DNA interstrand crosslinks

โœ Scribed by Kothandapani, Anbarasi; Patrick, Steve M.

Book ID
121447068
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
434 KB
Volume
743-744
Category
Article
ISSN
0027-5107

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## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the