Evidence for antigenic distinctness of the Epstein-Barr virus-determined nuclear antigen and the herpesvirus papio-determined nuclear antigen
✍ Scribed by Ohno, Shinsuke; Luka, Janos; Klein, George
- Book ID
- 123364128
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 213 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0304-3835
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## Abstract The purification of Epstein‐Barr virus‐determined nuclear antigen (EBNA) was attempted on the basis of its biochemical and physicochemical properties and its immunological specificity, assayed by the indirect single radial immunodiffusion test and anti‐complement immunofluorescence abso
## Abstract Low ionic strength (50 to 100 mM NaCl) and pH 6.0 were found to be optimal conditions for __in vitro__ conversion of Epstein‐Barr virus (EBV)‐determined nuclear antigen (EBNA)‐negative nuclei to EBNA‐positive nuclei by addition of the complement‐fixing (CF) antigen extracted from Raji c