Evidence for an early appearance of mode
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Maria Aveskogh; Lars Hellman
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Article
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1998
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John Wiley and Sons
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English
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In birds, reptiles and amphibians the IgY isotype exhibits the functional characteristics of both of IgG and IgE. Hence, the gene for IgY most likely duplicated some time during early mammalian evolution and formed the ancestor of present day IgG and IgE. To address the question of when IgY duplicat