Evidence for an Akt-kinase/NO/cGMP pathway in the cochlea of guinea pigs
✍ Scribed by Alexander Hess; Daniel Labbé; Ken-Ichi Watanabe; Wilhelm Bloch; Olaf Michel
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 311 KB
- Volume
- 263
- Category
- Article
- ISSN
- 0302-9530
No coin nor oath required. For personal study only.
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## Abstract The NO‐cGMP pathway has emerged as a neuroprotective signaling system involved in communication between neurons and glia. We have previously shown that axotomy or nerve growth factor (NGF)‐deprivation of dorsal root ganglion (DRG) neurons leads to increased production of NO and at the s
Nonadrenergic noncholinergic (NANC) relaxations of the guinea pig trachea are thought to be mediated by vasoactive intestinal peptide (VIP) and nitric oxide (NO). Physiological studies have indicated that the parasympathetic ganglion neurons mediating NANC relaxations of the guinea pig trachea but n