Evidence for a Type 1 Diabetes Susceptibility Locus (IDDM10) on Chromosome 10p11-q11 in a Russian Population
β Scribed by D. A. Chistiakov; Y. Seryogin; K. V. Savost'anov; L. I. Zilberman; E. V. Titovich; T. L. Kuraeva; I. I. Dedov; V. V. Nosikov
- Book ID
- 110749658
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 108 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0300-9475
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## Abstract ## Background Oxidative stress is involved in the origin of type 1 diabetes. Low efficiency of the scavenging antioxidant system has been shown to be related to the pathogenesis of the disease. This, therefore suggests that genes encoding catalase and other antioxidant enzymes may impl
## Recent reports on potential linkage by Faraone and the NIMH Genetics Initiative-Millennium Schizophrenia Consortium [1997: Am J Med Genet 74:557], and by Straub et al. [1997: Am J Med Genet 74:558], prompted us to study chromosome 10 in a sample of 72 families containing 2 or more affected sibs