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Evidence for a Role of Phosphatidylinositol 3-Kinase in IL-4-Induced Germline Cϵ Transcription

✍ Scribed by Koichi Ikizawa; Keiichi Kajiwara; Yuji Basaki; Takehiro Koshio; Yukiyoshi Yanagihara


Book ID
112239545
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
233 KB
Volume
170
Category
Article
ISSN
0008-8749

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In the present study we have investigated the potential involvement of protein kinase C (PKC) in the maturation of human dendritic cells (DC) by bacterial lipopolysaccharide (LPS). LPS stimulation of DC derived from human monocytes resulted in PKC phosphorylation. Inhibition of PKC activation using