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Evidence for a role of glucuronosyltransferase in the regulation of androgen action in the human prostatic cancer cell line LNCaP

✍ Scribed by Guillemette, Chantal; Hum, Dean W.; Bélanger, Alain

Book ID: 123045102
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 598 KB
Volume: 57
Category: Article
ISSN: 0960-0760
DOI: 10.1016/0960-0760(95)00258-8

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## Abstract Insulin‐like growth factor binding protein‐3 (IGFBP‐3), an antiproliferative and proapoptotic protein, has been shown to be upregulated by growth inhibitory concentrations of androgens in LNCaP human prostate cancer (PCa) cells, but the mechanism of regulation and the role of IGFBP‐3 in