Evidence for a predisposition to rheumatic diseases in families of patients developing drug-induced systemic lupus erythematosus

Sequential development of antibodies to

Sequential development of antibodies to specific sm polypeptides in a patient with systemic lupus erythematosus: evidence for independent regulation of anti—double-stranded dna and anti-sm antibody production

✍ E. J. Ter Borg; G. Horst; E. Hummel; D. Jaarsma; P. C. Limburg; C. G. M. Kallenb 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 2 views

We describe a patient with systemic lupus erythematosus who, after a disease flare, sequentially produced antibodies to specific Sm polypeptides (demonstrated by counterimmunoelectrophoresis, immunoblotting, and RNA immunoprecipitation) concomitantly with the disappearance of anti-double-stranded DN